Ureaplasma isolates recovered from neonates in England 1 and Wales between 2007 to 2013
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چکیده
18 Ureaplasma are associated with numerous clinical sequelae with treatment options being limited due 19 to patient and pathogen factors. This report examines the prevalence and mechanisms of antibiotic 20 resistance among clinical strains isolated from 95 neonates, 32 women attending sexual health clinic 21 and 3 patients under investigation for immunological disorders, between 2007 – 2013 in England and 22 Wales. Minimum inhibitory concentration was determined by using microbroth dilution assays, and a 23 subset of isolates were compared using broth microdilution method and Mycoplasma-IST2 assay. 24 The underlying molecular mechanisms for resistance were determined for all resistant isolates. Three 25 isolates carried the tet(M) tetracycline resistance gene (2.3% CI+2.58); two isolates were 26 AAC Accepted Manuscript Posted Online 12 October 2015 Antimicrob. Agents Chemother. doi:10.1128/AAC.00889-15 Copyright © 2015, American Society for Microbiology. All Rights Reserved.
منابع مشابه
Antibiotic Resistance among Clinical Ureaplasma Isolates Recovered from Neonates in England and Wales between 2007 and 2013.
Ureaplasma spp. are associated with numerous clinical sequelae with treatment options being limited due to patient and pathogen factors. This report examines the prevalence and mechanisms of antibiotic resistance among clinical strains isolated from 95 neonates, 32 women attending a sexual health clinic, and 3 patients under investigation for immunological disorders, between 2007 and 2013 in En...
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تاریخ انتشار 2015